Workshop on population Pharmacokinetics
(30/05/2014)
A 2-day workshop focussing on pharmacokinetic modeling and population approach. The major purpose of the workshop is to provide the participants the most basic knowlegdes and technical details about pharmacokinetic models, population approach. Typical uses of modeling methodologies in drug development, clinical studies will be explored in this meeting.
Dates: 30 – 31 May 2014
Organising
Committee:
Colin Pillai, Global Head, Scientific Capability
Development, Novartis, Switzerland
Vu Van Ai Khanh,
Scientific Chief Officer, Novartis Vietnam
France Mentre, Professor of
Biostatistics, University of Paris Diderot, France
Emmanuelle Comets, Lecturer,
University of Paris/INSERM, France
Nguyen Lien Huong,
Head of, Hanoi University of Pharmacy
Vu Dinh Hoa, assistant professor, Clinical
Pharmacy Department, Hanoi University of
Pharmacy
Thi Huyen Tram NGUYEN, PhD
Student, INSERM, University of Paris Diderot, France
Faculty:
Colin Pillai, Global Head,
Scientific Capability Development, Novartis, Switzerland
France Mentre, Professor of
Biostatistics, University of Paris Diderot, France
Emmanuelle Comets, Lecturer,
University of Paris/INSERM, France
Nguyen Lien Huong,
Head of, Hanoi University of Pharmacy
Vu Dinh Hoa, assistant professor, Clinical
Pharmacy Department, Hanoi University of
Pharmacy
Thi Huyen Tram NGUYEN, PhD
Student, INSERM, University of Paris Diderot, France
Participants: Researchers from
several Medical Universities with an interest in Pharmacokinetic modeling
AGENDA
TIME
|
TOPIC
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PIC
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DAY 1 - May 30, 2014
|
9:45 – 10:00
|
Welcome and meeting opening
|
Hanoi Faculty Members
|
10:00 – 10:30
|
Introduction to
PKPD modeling
With video
|
Colin Pillai
|
10:30 – 11:30
|
Introduction to
Population PK
|
France Mentré
|
11h30-12h30
|
Models and
estimation methods
|
Emmanuelle Comets
|
12:30 – 14:00
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Lunch
|
|
14:00 – 17:00
|
Pre-workshop: library of PK models
Warfarin PK
Workshop 1: Model building using MONOLIX
software
Model building, evaluation…
Data: Warfarin data
Software: MONOLIX has to be installed before on
personal computers of participants
|
France Mentré
Colin Pillai
Emmanuelle Comets
Tram Nguyen
|
DAY 2 - May 31, 2014
|
8:30 – 10:00
|
Covariate PK
Modeling & Pharmacogenetics
|
Emmanuelle
Comets
|
10:00 – 10:30
|
Coffee Break
|
|
10:30 – 11:30
|
Uncertainty and Variability
|
France Mentré
|
11:30– 12:15
|
A
pharmacokinetic – viral kinetic model to explain virologic response to
alisporivir and peg-IFN
|
Tram Nguyen
|
12:15 – 13:45
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Lunch
|
|
13:45 – 16:00
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Workshop 2 – Covariate modeling & model evaluation (cont.)
|
France Mentré
Colin Pillai
Emmanuelle Comets
Tram Nguyen
|
16:00 – 17:00
|
Discussion
|
|